Acquired Resistance to Antituberculosis Drugs
نویسندگان
چکیده
منابع مشابه
Acquired Resistance to Antituberculosis Drugs in England, Wales, and Northern Ireland, 2000–2015
Among tuberculosis (TB) patients, acquired resistance to anti-TB drugs represents a failure in the treatment pathway. To improve diagnosis and care for patients with drug-resistant TB, we examined the epidemiology and risk factors associated with acquired drug resistance during 2000-2015 among TB patients in England, Wales, and Northern Ireland. We found acquired resistance in 0.2% (158/67,710)...
متن کاملMycobacterium tuberculosis resistance to antituberculosis drugs in Mozambique*, **
OBJECTIVE To determine the drug resistance profile of Mycobacterium tuberculosis in Mozambique. METHODS We analyzed secondary data from the National Tuberculosis Referral Laboratory, in the city of Maputo, Mozambique, and from the Beira Regional Tuberculosis Referral Laboratory, in the city of Beira, Mozambique. The data were based on culture-positive samples submitted to first-line drug susc...
متن کاملPrimary drug resistance of Mycobacterium tuberculosis to antituberculosis drugs.
Thirty two positive sputa from 104 untreated cases of pulmonary tuberculosis, were tested for sensitivities against antituberculosis drugs. Twenty four were positive on direct smear as well as culture while 8 were only culture positive. Nine (28%) were resistant to Isoniazid, 3 (9.4%) to Streptomycin and 2 (6.3%) were resistant to both the drugs. All the 32 were sensitive to Rifampicin and Etha...
متن کاملAntituberculosis drugs and hepatotoxicity.
Isoniazid, pyrazinamide and rifampicin have hepatotoxic potential, and can lead to such reactions during antituberculosis chemotherapy. Most of the hepatotoxic reactions are dose-related; some are, however, caused by drug hypersensitivity. The immunogenetics of antituberculosis drug-induced hepatotoxicity, especially inclusive of acetylaor phenotype polymorphism, have been increasingly unravell...
متن کاملExtent and origin of resistance to antituberculosis drugs in the Netherlands, 1993 to 2011.
The elimination of tuberculosis (TB) is threatened by an apparent increase in the level of resistance in Mycobacterium tuberculosis. In the Netherlands, where the majority of TB patients are migrants, resistance may also be increasing. We conducted a retrospective study, using 18,294 M. tuberculosis isolates from TB cases notified between 1993 and 2011. We investigated the trends in antitubercu...
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ژورنال
عنوان ژورنال: Emerging Infectious Diseases
سال: 2018
ISSN: 1080-6040,1080-6059
DOI: 10.3201/eid2411.180465